Amgen pleads guilty, to settle misbranding case for $762 million













Amgen


Drugmaker Amgen Inc. of Thousand Oaks reached a settlement Tuesday in a federal investigation of its sales and marketing practices.
(Paul Sakuma / Associated Press / December 17, 2012)































































Biotech giant Amgen Inc. pleaded guilty to a federal misdemeanor of misbranding its anemia drug Aranesp and has agreed to pay $762 million in fines and penalties.


The Thousand Oaks company said it had reached a preliminary settlement of federal criminal and civil investigations last year and had already set aside about $780 million to resolve several related cases.


A spokesman for the U.S. attorney's office in Brooklyn said a federal judge is scheduled to hold another hearing on the settlement Wednesday.





Amgen said the "plea and sentence remain subject to judicial review and approval" and it expects to resolve the related civil and criminal matters once that process is complete.


Federal prosecutors accused Amgen of promoting Aranesp for uses that weren't approved by the U.S. Food and Drug Administration, a common claim brought by government officials against big pharmaceutical companies.


Amgen's shares were up 7 cents to $89.57 in mid-session trading Tuesday.


Aranesp, which is used primarily to treat anemia in cancer patients, generated sales of $2.3 billion last year. But sales of Amgen's anemia treatments have slumped in recent quarters due partly to safety concerns.


In recent years, federal prosecutors have aggressively pursued whistleblower fraud cases against large drug makers and won major settlements.


In July, GlaxoSmithKline agreed to plead guilty to federal charges and pay $3 billion in the largest healthcare-fraud settlement in U.S. history.


However, some critics say the government's enforcement efforts don't go far enough since the company executives involved usually don't face significant penalties or jail time.


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Follow Chad Terhune on Twitter






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U.S. moves ahead on new downtown L.A. courthouse









Downtown Los Angeles is finally getting its new federal courthouse, and it's going to stand out amid the aging government buildings in the Civic Center.


A 550,000-square-foot courthouse — planned for the southwest corner of Broadway and 1st Street, across from the old county law library and the Los Angeles Times building — will feature a bright, serrated facade and a structural design that allow the structure to appear to float over its stone base, officials said.


It will have a public plaza along 1st Street near recently opened Grand Park. Officials say the building's design has received a "platinum" rating for energy efficiency from the U.S. Green Building Council.





The U.S. General Services Administration is moving forward on the project despite last-minute opposition from some Republicans in Congress, who question the viability of the agency's plans to sell the federal courthouse on North Spring Street to private developers. The lawmakers also questioned whether the extra courtrooms were actually necessary.


The GSA awarded a $318-million contract last week to the architecture firm Skidmore, Owings & Merrill and Clark Construction Group, and released several renderings of the proposed design. The building will rise on a 3.6-acre lot on Broadway that city officials have long wanted to develop.


"We are moving toward the groundbreaking of a critically needed facility that will resolve long-standing security and space issues," Rep. Lucille Roybal-Allard (D-East Los Angeles) said in a statement. "At a time when we need to keep investing in our recovering economy, we expect the courthouse to create thousands of new jobs in the construction industry and related businesses."


Peter Zellner, faculty member at Southern California Institute of Architecture, noted that the courthouse design in some ways is reminiscent of Mid-Century architectural styles of other Los Angeles government centers, particularly the Wilshire Federal Building. Zellner also suggested the architects consider the courthouse plaza as part of a chain of public spaces spilling down from the Walt Disney Concert Hall.


The courthouse will include 24 courtrooms and 32 judicial chambers. Along with the judges of the U.S. District Court, the building will be used by the U.S. Marshals Service, U.S. attorneys' office and the Federal Public Defender.


Federal judges have been pushing for new space downtown since the late 1990s. In addition to the Spring Street courthouse, federal judges occupy space elsewhere in downtown, but they have complained about overcrowding and security issues.


Construction on the courthouse is expected to begin sometime next year, with completion set for 2016, the GSA said.


The agency also announced that it had released a formal "request for information" to solicit ideas for adaptive reuse of one of the old federal courthouses, on North Spring Street. Under the agency's plan, the 72-year-old building would be sold to a private developer, with the proceeds to help finance construction of a second federal office building next to the new courthouse.


Some real estate experts have questioned whether the exchange proposal would be feasible, saying it could be difficult for a private owner to adapt the old courthouse because of its structural issues, location and historic status. And the Republican critics of the courthouse plan expressed concern that if the GSA could not manage to sell the old courthouse, it would be stuck with a vacant building and higher costs to taxpayers.


There is still no specific timeline on when the exchange would be made, a GSA spokeswoman said, but officials remain upbeat about the plan.


"This step is just another example of GSA's commitment to providing real value to the American public," said acting GSA Administrator Dan Tangherlini.


sam.allen@latimes.com





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RIM begins BlackBerry 10 tests with business, government clients






TORONTO (Reuters) – Research In Motion Ltd said on Monday that it had begun a “beta testing” program that allows 120 companies and government departments to try out its new BlackBerry 10 smartphones before their global launch on January 30.


The Canadian company, which is trying to reverse a sharp decline in market share for the BlackBerry, said the program would enable so-called enterprise customers in business and government to size up the BB10.






Features of the BB10 include the ability to separate personal and business information so that the user can store both without compromising security.


RIM has struggled in recent years to hold on to its base of enterprise customers, which typically pay a higher subscription fee than consumers, as their employees push to use devices such as Apple Inc’s iPhone for business as well as personal communications.


“This is a crucial step for us in getting our large enterprise customers ready to support BlackBerry 10 at the point of launch date, as opposed to post-launch date,” Bryan Lee, senior director for enterprise accounts, said in a phone interview.


RIM is providing the software and handsets at no charge, and the companies do not have to buy anything once the trial is finished.


The company plans to release its quarterly results on Thursday, and analysts expect it to report its third straight loss as it struggles to sell its older devices.


RIM made its name selling mobile email devices to bankers, lawyers and other professionals before expanding to sell phones to consumers.


The company said the BB10 testers were from financial, insurance, healthcare, manufacturing, media, and distribution industries and include 64 Fortune 500 companies, as well as government departments.


Lee would not identify any of the entities, beyond Integris Health and the U.S. Immigration and Customs Enforcement agency, which have both said they are testing the new devices.


The customers have installed test versions of RIM’s new server software, which manages iPhones and devices using Google Inc’s Android software as well as BlackBerrys, and will each receive two preproduction BlackBerry 10 handsets later this week.


RIM shares were down 2.1 percent at C$ 13.59 in morning Toronto Stock Exchange trading.


The stock has rallied from September’s multiyear lows around C$ 6.50 on a wave of optimism over the new devices, but the share price is still far below mid-2008 highs of around C$ 150.


(Reporting by Alastair Sharp; Editing by Lisa Von Ahn)


Tech News Headlines – Yahoo! News





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Beck looks for new connection with 'Song Reader'


NASHVILLE, Tenn. (AP) — Beck Hansen wants you to think about the way music has changed over the last century and what that means about how human beings engage each other these days.


Laboring over the intricate and ornate details of his new "Song Reader" sheet music project, he was struck by how social music used to be — something we've lost in the age of ear buds.


"You watch an old film and see how people would dance together in the '20s, '30s and '40s. You'd go out and people would switch partners and it was a way of social interaction," Hansen said. "It's something that was part of what brought people together. Playing music in the home is another aspect of that that's been lost. Again, I'm not on a campaign to get people to take up songs and play music in their home or anything. But it is interesting to me, the loss of that, what it means."


Beck hopes the "Song Reader" inspires some of us to pick up instruments and limber our vocal cords. It includes 20 songs annotated on sheet music that's been decorated in the style popular in the early 20th century when the songwriting industry was a thriving enterprise with billions of songs sold.


The 42-year-old singer notes in the book's preface that Bing Crosby's "Sweet Leilani" sold an estimated 54 million copies in 1937, meaning about 40 percent or more of the U.S. population was engaged in learning how to play that song. They were touching it directly, speeding it up, slowing it down, changing the lyrics and creating something new.


"There's popular bands now that people know the words to their songs and can sing along, but there's something about playing a song for yourself or for your friends and family that allows you to inhabit the song and by some sort of osmosis it becomes part of who you are in a way," he said. "So when I think of my great-grandparents' generations, music defined their lives in a different way than it does now."


Beck proposed the idea to McSweeney's Dave Eggers in 2004 and it soon blossomed into something more ambitious as the artist wrapped his mind around the challenge of not just writing a song, but presenting it in a classic way that also engages fans who might not be able to read music or play their own instruments.


They quickly agreed it would make no money, but it seemed like an idea worth exploring.


"And it seemed like only Beck would have thought of it," Eggers said in an email to the Associated Press. "It's a very generous project, in that he wrote a bunch of songs and just gives them to the world to interpret. That's a very expansive kind of generosity and inclusiveness that we're happy to be part of. On a formal level, we love projects like this, that are unprecedented, and that result in a beautiful object full of great art and great writing. And it all started with Beck. It's a testament to his groundbreaking approach to everything he does."


Beck hopes fans will record their own versions and upload them to the Internet so those songs grow into something more universal.


As for his own recorded music, that's a little more complicated.


Beck's not sure where he's headed at the moment. He recorded an album in 2008, but set it aside to work with Charlotte Gainsbourg on "IRM," which he wrote and produced. He's also been writing songs for soundtracks and special projects and producing artists like Thurston Moore, Stephen Malkmus and Dwight Yoakam. All that has left him feeling creatively satisfied, but he does acknowledge it's been a while since he released 2008's Danger Mouse-produced "Modern Guilt."


He says in many ways he's reached a crossroads he's not yet sure how to navigate.


"This last year I've been thinking about whether I'd finish those songs (from 2008), whether they're relevant or worthy of releasing. I know that doesn't sound very definitive," he said, laughing, "but that's the kind of place I'm in — in this kind of limbo — and, um, yeah."


The "Song Reader" spurred Beck to think about his own work in a new light as well. Spending six months finishing off the project after working on it sporadically over the years, he was struck by how much craft went into the creation of each song and how quickly music can come into existence today.


"There is so much music out there, to me," he said. "I don't know if it's just where I am in my own music making or if it's a product of the amount of music out there, but I feel like a piece of music does have to have a certain validity to be put out there and to ask people to listen. ... I feel like it's impossible for everyone to keep up, you know, so I guess I've been feeling like maybe there's something to picking what you're going to put out, about being more particular about what you put out."


___


Online:


http://beck.com


___


Follow AP Music Writer Chris Talbott: http://twitter.com/Chris_Talbott.


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The New Old Age Blog: In the Middle: Why Elderly Couples Fight

George and Gracie (let’s call them that because using their real names would make them even unhappier than they already appear to be) are in their 80s and have been married for more than 65 years. Until recently they seemed to ride the waves that are inevitable in any marriage that spans nearly seven decades; through good and bad, they were partners and best friends.

But lately — ever since her hospitalization and his fall — they have been arguing more bitterly than usual (“Do you have to make such a mess in the kitchen?”), criticizing each other (“Why haven’t you dealt with the insurance company yet?”), withdrawing from each other, and generally making each other more miserable, more often than ever before.

This kind of degenerative relationship is not uncommon among the elderly in even the happiest marriages, marriage therapists and geriatricians said. But that is small comfort to either the couple in the middle of the maelstrom, or the children who care for them, as evidenced by a number of postings on caregiver blogs. As some of the children have wondered there: “Why can’t we all just get along?”

Therapists and others who work with the elderly said the first step to addressing the problem is understanding where it came from.

“A key question is whether the marital bickering is part of a lifelong marital style or a change,” said Dr. Linda Waite, director of the Center on Demography and Economics of Aging at NORC/University of Chicago. Is it new behavior – or just new to the grown children who are suddenly so deeply enmeshed in their parents’ lives that they are only now noticing that something is amiss?

How much of the problem is really just the marriage style? “Some couples like to fight and argue – it keeps their adrenaline going,” said Dr. Nancy K. Schlossberg, professor emerita of counseling psychology at the University of Maryland and author of “Overwhelmed: Coping With Life’s Ups and Downs.”

Sometimes the best judges of whether there is a problem are outsiders, said Dr. William Dale, chief of geriatrics at the University of Chicago Geriatrics Medicine. Pay attention if someone says, “‘Gee, Mom seems more argumentative or withdrawn than the last time I saw her,’” Dr. Dale advised.

If the tone or severity of the marital tensions seem new, then it is important to find out why. The causes could be mental or physical, doctors say.

On the mental front, increased anger and fighting could be one of the first signs of mild cognitive impairment, a precursor of dementia or Alzheimer’s, in one or both of the spouses, said Dr. Lisa Gwyther, director of the Duke Center for Aging Family Support Program and an associate professor in the department of psychiatry and behavioral sciences.

Dr. Dale concurs: “There is good evidence that the earliest signs of cognitive impairment are often emotional changes” — anger, anxiety, depression — “rather than cognitive ones” — memory, abstract thought.

But these early signs of cognitive decline can be so subtle that neither the spouses themselves, or their grown children, recognize them for what they are, Dr. Gwyther said. So husband and wife blame each other for the changes and allow feelings of hurt and resentment to grow.

Withdrawing from activities that used to give them pleasure can be a telltale sign of mild cognitive impairment – and can trigger anger and arguments.

“In one couple, the husband just didn’t want to participate in the holidays — the wife got angry and said he was being lazy and stubborn,” said Dr. Gwyther. But the truth was that his cognitive decline made all the activity overwhelming, and he didn’t want anyone to know that he was anxious about not remembering everyone’s names and embarrassing himself.

Suspicion and paranoia can also accompany mild cognitive decline and precipitate distrust and hurtful accusations. Dr. Gwyther recalled another woman who “called her daughter frantic because she said her husband dropped her at her chemo appointment, went to park the car, and didn’t return to get her.” The woman couldn’t imagine that her husband could possibly have lost his sense of time and direction, Dr. Gwyther added. She took it personally, complaining to her daughter that “your father doesn’t seem to care any more.”

Dr. Dale told of a spouse who accused her mate of infidelity because “she was convinced that when he was out grocery shopping he was really having an affair.”

Hoarding, an early symptom of mild cognitive impairment, can also create tension in a marriage. (For new treatments, see this recent post by my colleague Paula Span.)

When one couple came to a counseling session with Dr. Norman Abeles, emeritus professor of psychology and former director of psychological clinic at Michigan State University, the hoarding spouse finally said she did it because she thought that they would run out of money, “even though there was enough money to go around.” Dr. Abeles said that incident led to her diagnosis of mild cognitive impairment.

Adding to the confusion, mild cognitive impairment, or M.C.I., comes and goes. “There are good days and bad days, good hours and bad hours,” said Dr. Gwyther. “Alzheimer’s and dementia don’t start on Tuesday — it’s a slow insidious onset.” But the diagnosis is becoming more common: The Institute for Dementia Research and Prevention predicts that 1 in 6 women, and 1 in 10 men, who live past the age of 55 will develop dementia in their lifetime.

“Spouses find it difficult to know when their partner with M.C.I. is acting differently, usually badly, due to the advancing illness or due to ‘willful’ personality issues,” said Dr. Dale, citing a 2007 study in the journal Family Relations exploring the problems this can create for couples.

Blaming is often easier than understanding. Another of Dr. Gwyther’s patients was furious at her husband for not filing their taxes. “He’s a C.P.A.,” she said. “How could we owe back taxes?” It did not occur to her that he might be unable to handle that task — and was too frightened about his deteriorating mental focus to let her know.

But as harmful as mental decline can be for a marriage, it is just part of the equation. Physical ailments – even those that seem completely unrelated to marital relations – “can upset the equilibrium of the marriage,” according to a study in The Canadian Medical Association Journal.

“Most men get angry at what’s happened to them when they get ill, women get angry and scared when he’s not what he used to be — so they fight,” said Dr. Schlossberg.

Chronic illnesses, like diabetes, arthritis and heart disease, can have a strong negative effect on mood, said Dr. Waite, who will soon be publishing a study on the subject. Diabetes is so often accompanied by depression that Dr. Waite said “one of my colleagues argues that that it is even part of the disease.”

And ailments can have an effect on a couple’s sex life — which can compound the marital problems, doctors said.

“Diabetes brings on neuropathy,” said Dr. Waite. “That means touching and feeling in sex is not as rewarding.” Without the pleasures of affectionate touching — whether a passing hug at the sink or more — tensions can build. That’s why, if a couple is having problems with sex, they are more likely to have problems in the relationship — and vice versa, according to a 2007 New England Journal of Medicine study of sex and health among older adults.

Other changes in circumstances — retirement, shifting roles, the loss of autonomy, disparities in health and abilities — can wreak havoc. Losing independence can feel like losing oneself — and if you don’t know who you are any more, how can you know how to relate to your spouse?

“Fighting may come from a misguided notion that you can regain power by asserting it over your spouse,” said Dr. Schlossberg, whose observations are echoed in a 1984 study in The Canadian Journal of Medicine. “It doesn’t work, it’s false power – but they’ll try anything.”

The sheer exhaustion that can come from being the caregiving spouse is also bound to “make them stressed and angry,” said Dr. Waite. Not to mention guilty and resentful — never a prescription for happy marital relations.

“Part of the trap for the caregiver is the idea that you have to do it all, and the guilt you feel when you cannot live up to it,” said Dr. Gordon Herz, a psychologist in private practice in Madison, Wisc. Not surprisingly, resentment can soon follow, Dr. Herz added, because it is hard to admit to anyone that, “‘this is too much for me.’”

What can outside caregivers — children or other loved ones — do about these golden marriages on the rocks? Should they intervene — or butt out? And can marital therapy help — or is it too late to change?


Share your thoughts and experiences — and on Tuesday we will try to provide some advice from experts.

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Santa Ana-based Edison Mission Energy files for bankruptcy









Edison Mission Energy, an unregulated power-generating unit of Rosemead-based Edison International, said Monday that it had filed for bankruptcy and had agreed on a reorganization plan with its parent company and holders of its $3.7 billion in debt.


 “We are pleased to have reached this agreement, which we believe reflects the long-term value potential of our organization,” Pedro Pizarro, president of Edison Mission Energy, said in a statement. “This is an important first step in the process to reduce our debt, enhance our liquidity profile and position EME for continued operation and future success."


As part of the deal, Edison Mission Energy will be deconsolidated from Edison International “as of the filing date” and, in the future, will be referred to by the parent company as discontinued operations.





Edison International’s stake in the bankrupt generating unit will be transferred to unsecured creditors.


Santa Ana-based Edison Mission Energy said it had slightly more than $5.1 billion in assets and just under that amount in liabilities in Chapter 11 papers filed Monday in the U.S. Bankruptcy Court in the Northern District of Illinois.


Edison Mission Energy has been struggling on several fronts: depressed energy prices because of the nation’s boom in natural gas production; higher fuel costs affecting its older coal-fired facilities; and pending debt maturities.


The company also said, in the statement, that it faced the “need to retrofit its coal-fired facilities to comply with environmental regulations.”


Despite the challenges, Pizarro sought to strike a positive tone on Edison Mission Energy’s future.


“We believe this financial restructuring — coupled with the existing strength of our employees and assets — will position us to take advantage of new opportunities while preserving our focus on safe, reliable operations,” Pizarro said.


Edison Mission Energy companies own, operate and lease a portfolio of more than 40 electric generating sites around the U.S. that are powered by wind, natural gas, biomass and coal, as well as an energy marketing and trading operation based in Boston.


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Speculation over autism, but shooter's 'why' has no easy answer









Among the details to emerge in the aftermath of the Connecticut elementary school massacre was the possibility that the gunman had some form of autism.


Adam Lanza, 20, had a personality disorder or autism, his brother reportedly told police. Former classmates described him as socially awkward, friendless and painfully shy.


While those are all traits of autism, a propensity for premeditated violence is not. Several experts said that at most, autism would have played a tangential role in the mass shooting -- if Lanza had it at all.





FULL COVERAGE: Connecticut school shooting


“Many significant psychiatric disorders involve social isolation,” said Catherine Lord, director of the Center for Autism and the Developing Brain at New York-Presbyterian Hospital.


Autism, she said, has become a catch-all term to describe anybody who is awkward.


Some type of schizophrenia, delusional disorder or psychotic break would more clearly fit the crime, experts said.


The hallmark characteristics of autism are social inability, communication problems and repetitive behaviors or obsessive interests. It emerges in early childhood and exists on a vast spectrum, from those who bang their head against the wall to those who can recite train schedules from memory.


PHOTOS: Connecticut school shooting


The rate of autism has skyrocketed over the last two decades, largely because of an expanded definition of the disorder and increasing awareness. The U.S. Centers for Disease Control and Prevention estimates that 1 in 88 children have it.


Researchers have struggled to draw clear lines between the various forms. As a result, the American Psychiatric Assn. is folding all of its varieties into a single diagnosis next year: autism spectrum disorder.


It will include people with Asperger’s syndrome -- the higher-functioning type that Lanza was most likely to have had.


There is more aggression associated with autism than with other disabilities. But it usually amounts to a tantrum and does not involve planning, weapons or an intention to harm anybody.


People with autism are more likely to be victims of violence than perpetrators. Those who are bright -- as Lanza was by several accounts -- often face bullying.


Some wind up in trouble with the law because they are unaware of social convention, and quirkiness or attempts at being friendly get misinterpreted.


Dr. John Constantino, an autism specialist at Washington University in St. Louis, said the social detachment and withdrawal associated with the disorder can accentuate other psychiatric conditions that are connected to violence.


And the feelings of isolation often intensify after high school, with the loss of a structured environment that allows many people with autism to stay afloat.


“They sort of fall off this cliff when they don’t have a village,” Constantino said.


Lanza finished high school early and was living with his mother. Police said he was disturbed by the divorce of his parents in 2009.


None of that, of course, explains why his killed his mother, 20 elementary school students, six women at the school and then himself.


“The only way somebody could do something like this is if they totally lost touch with reality,” said Dr. Daniel Geschwind, an autism expert at UCLA. “Autistic people are not sociopaths.”


ALSO:


Suspect in massacre tried to buy rifle days before, sources say


In Newtown, death's chill haunts the morning after school shooting


Connecticut shooting: Gunman forced his way into school, police say


alan.zarembo@latimes.com



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'The Hobbit' tops box office with $84.8 million


NEW YORK (AP) — Peter Jackson's "The Hobbit" led the box office with an opening of $84.8 million, a start better than the three previous "Lord of the Rings" films.


Studio estimates Sunday had the Warner Bros. 3-D epic as the biggest December opening ever, surpassing Will Smith's "I Am Legend," which opened with $77.2 million in 2007.


Despite generally poor reviews, the adaptation of J. R. R. Tolkien's first novel in the fantasy series was an even bigger draw than the last "Lord of the Rings" films, "The Return of the King." That film opened with $72.6 million.


While Jackson's "Rings" movies drew many Oscar nominations, the path for "The Hobbit" has been rockier. It received no Golden Globes nominations on Thursday. Its 48-frames-per-second, double the usual rate, also has been criticized.


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Dr. William F. House, Inventor of Cochlear Implant, Dies





Dr. William F. House, a medical researcher who braved skepticism to invent the cochlear implant, an electronic device considered to be the first to restore a human sense, died on Dec. 7 at his home in Aurora, Ore. He was 89.




The cause was metastatic melanoma, his daughter, Karen House, said.


Dr. House pushed against conventional thinking throughout his career. Over the objections of some, he introduced the surgical microscope to ear surgery. Tackling a form of vertigo that doctors had believed was psychosomatic, he developed a surgical procedure that enabled the first American in space to travel to the moon. Peering at the bones of the inner ear, he found enrapturing beauty.


Even after his ear-implant device had largely been supplanted by more sophisticated, and more expensive, devices, Dr. House remained convinced of his own version’s utility and advocated that it be used to help the world’s poor.


Today, more than 200,000 people in the world have inner-ear implants, a third of them in the United States. A majority of young deaf children receive them, and most people with the implants learn to understand speech with no visual help.


Hearing aids amplify sound to help the hearing-impaired. But many deaf people cannot hear at all because sound cannot be transmitted to their brains, however much it is amplified. This is because the delicate hair cells that line the cochlea, the liquid-filled spiral cavity of the inner ear, are damaged. When healthy, these hairs — more than 15,000 altogether — translate mechanical vibrations produced by sound into electrical signals and deliver them to the auditory nerve.


Dr. House’s cochlear implant electronically translated sound into mechanical vibrations. His initial device, implanted in 1961, was eventually rejected by the body. But after refining its materials, he created a long-lasting version and implanted it in 1969.


More than a decade would pass before the Food and Drug Administration approved the cochlear implant, but when it did, in 1984, Mark Novitch, the agency’s deputy commissioner, said, “For the first time a device can, to a degree, replace an organ of the human senses.”


One of Dr. House’s early implant patients, from an experimental trial, wrote to him in 1981 saying, “I no longer live in a world of soundless movement and voiceless faces.”


But for 27 years, Dr. House had faced stern opposition while he was developing the device. Doctors and scientists said it would not work, or not work very well, calling it a cruel hoax on people desperate to hear. Some said he was motivated by the prospect of financial gain. Some criticized him for experimenting on human subjects. Some advocates for the deaf said the device deprived its users of the dignity of their deafness without fully integrating them into the hearing world.


Even when the American Academy of Ophthalmology and Otolaryngology endorsed implants in 1977, it specifically denounced Dr. House’s version. It recommended more complicated versions, which were then under development and later became the standard.


But his work is broadly viewed as having sped the development of implants and enlarged understanding of the inner ear. Jack Urban, an aerospace engineer, helped develop the surgical microscope as well as mechanical and electronic aspects of the House implant.


Karl White, founding director of the National Center for Hearing Assessment and Management, said in an interview that it would have taken a decade longer to invent the cochlear implant without Dr. House’s contributions. He called him “a giant in the field.”


After embracing the use of the microscope in ear surgery, Dr. House developed procedures — radical for their time — for removing tumors from the back portion of the brain without causing facial paralysis; they cut the death rate from the surgery to less than 1 percent from 40 percent.


He also developed the first surgical treatment for Meniere’s disease, which involves debilitating vertigo and had been viewed as a psychosomatic condition. His procedure cured the astronaut Alan B. Shepard Jr. of the disease, clearing him to command the Apollo 14 mission to the moon in 1971. In 1961, Shepard had become the first American launched into space.


In presenting Dr. House with an award in 1995, the American Academy of Otolaryngology-Head and Neck Surgery Foundation said, “He has developed more new concepts in otology than almost any other single person in history.”


William Fouts House was born in Kansas City, Mo., on Dec. 1, 1923. When he was 3 his family moved to Whittier, Calif., where he grew up on a ranch. He did pre-dental studies at Whittier College and the University of Southern California, and earned a doctorate in dentistry at the University of California, Berkeley. After serving his required two years in the Navy — and filling the requisite 300 cavities a month — he went back to U.S.C. to pursue an interest in oral surgery. He earned his medical degree in 1953. After a residency at Los Angeles County Hospital, he joined the Los Angeles Foundation of Otology, a nonprofit research institution founded by his brother, Howard. Today it is called the House Research Institute.


Many at the time thought ear surgery was a declining field because of the effectiveness of antibiotics in dealing with ear maladies. But Dr. House saw antibiotics as enabling more sophisticated surgery by diminishing the threat of infection.


When his brother returned from West Germany with a surgical microscope, Dr. House saw its potential and adopted it for ear surgery; he is credited with introducing the device to the field. But again there was resistance. As Dr. House wrote in his memoir, “The Struggles of a Medical Innovator: Cochlear Implants and Other Ear Surgeries” (2011), some eye doctors initially criticized his use of a microscope in surgery as reckless and unnecessary for a surgeon with good eyesight.


Dr. House also used the microscope as a research tool. One night a week he would take one to a morgue for use in dissecting ears to gain insights that might lead to new surgical procedures. His initial reaction, he said, was how beautiful the bones seemed; he compared the experience to one’s first view of the Grand Canyon. His wife, the former June Stendhal, a nurse, often helped.


She died in 2008 after 64 years of marriage. In addition to his daughter, Dr. House is survived by a son, David; three grandchildren; and two great-grandchildren.


The implant Dr. House invented used a single channel to deliver information to the hearing system, as opposed to the multiple channels of competing models. The 3M Company, the original licensee of the House implant, sold its rights to another company, the Cochlear Corporation, in 1989. Cochlear later abandoned his design in favor of the multichannel version.


But Dr. House continued to fight for his single-electrode approach, saying it was far cheaper, and offered voluminous material as evidence of its efficacy. He had hoped to resume production of it and make it available to the poor around the world.


Neither the institute nor Dr. House made any money on the implant. He never sought a patent on any of his inventions, he said, because he did not want to restrict other researchers. A nephew, Dr. John House, the current president of the House institute, said his uncle had made the deal to license it to the 3M Company not for profit but simply to get it built by a reputable manufacturer.


Reflecting on his business decisions in his memoir, Dr. House acknowledged, “I might be a little richer today.”


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Don't impoverish yourself to pay kids' student loans








Dear Liz: I'm in my 50s. My kids have college loan debts that might total more than $200,000. I allowed them to take out loans because I expected to inherit $300,000 to help them pay off the debt. Now that inheritance will not happen.


I have $250,000 saved for retirement. When I'm 58 1/2 years old, I would like to pull that money out and pay some or all of these debts. Or use home equity. I've recently been downsized in employment, but I am looking to increase my income so I can help with their debt. Advice?


Answer: If your goal is to impoverish yourself so your kids will have to take care of you in your old age, by all means proceed with your plan. Otherwise, you need to rethink this.






You've been laid off in the middle of what should be your peak earning years. Older workers often have a tougher time than younger ones finding replacement jobs, even in a better economy than this one. You may not be able to replace your former income, which means you may not be able to add much to the amount you've already saved. You should be conserving your resources, including your home equity, and not squandering it repaying debts that aren't yours.


And "squandering" is the right word. You may be able to avoid paying federal and state tax penalties on withdrawals under certain conditions; distributions made after age 59 1/2 avoid the penalties, as do those made if you're "separated from service" if the job termination occurred in or after the year you turn 55. But you'll still owe income taxes on the withdrawal, and those can be considerable.


Your children are the ones who will benefit from their educations. Those educations should allow them to earn incomes to repay these loans. The amount of debt they've accrued might be excessive — you didn't specify how many kids, or whether this debt is being incurred pursuing undergraduate or graduate degrees. Ultimately, though, they will be in a better position to pay the debt than you are.


If you promised them help you can't deliver, sit down with them now to break the bad news and strategize on how they can finish their educations without incurring substantially more debt.


Your story also should serve as a cautionary tale for anyone counting on an inheritance to pay future bills. Until the money is in your bank account, it's not yours and shouldn't be part of your financial planning.


Refinancing mortgage in divorce may not be wise move


Dear Liz: My soon-to-be ex wants to refinance our mortgage to pay for renovations so we can sell it for more money. He also wants to take out some cash to pay off unsecured loans. (I have $11,000 in credit card debt, and he has over $50,000.) The house recently appraised for $310,000 and we owe $158,000 on it. Is it wise to refinance in this circumstance?


Answer: A cash-out refinance would be a risky maneuver even if you intended to stay married. Renovations rarely boost a home sale price enough to cover their cost. Also, home equity that's used to pay off credit card bills is often wasted, since the borrower never fixes the problem that led to overspending in the first place and simply runs up more debt. Since he would be getting the bulk of the benefit by having more of his debt paid off, you also would need to adjust the rest of your property settlement.


Often, the best and easiest solution in a divorce is to simply sell the house. You certainly wouldn't want to remain on a mortgage with an ex after the divorce was final, if you could possibly avoid it. A good divorce attorney can give you advice about how to proceed from here.


Make saving money automatic


Dear Liz: What's the easiest way to save money? I have the hardest time. I want to save, but I feel that I don't make enough to start saving.


Answer: The easiest way to save is to do it without thinking about it.


That usually means setting up automatic transfers either from your paycheck or from your checking account. If you have to think about putting aside money, you'll probably think of other things to do with that cash. If it's done automatically, you may be surprised at how fast the money piles up.


The second part of this equation is to leave your savings alone. If you're constantly dipping into savings to cover regular expenses, you won't get ahead.


People manage to save even on small incomes because they make it a priority. They "pay themselves first," putting aside money for savings before any other bills are paid. Start with small, regular transfers and increase them as you can.


Questions may be sent to 3940 Laurel Canyon, No. 238, Studio City, CA 91604 or by using the "Contact" form at asklizweston.com. Distributed by No More Red Inc.






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